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The S100B Protein Could Be Used as Adjuvant Diagnostic Tool in Acute Ischemic Stroke
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Min Hee Jung, Dong Hoon Lee, Chan Woong Kim
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Korean J Crit Care Med. 2011;26(4):217-220.
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DOI: https://doi.org/10.4266/kjccm.2011.26.4.217
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 Abstract
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- BACKGROUND
In the emergency department, the diagnosis of ischemic stroke is difficult because the diagnostic modalities are limited to non-contrast brain CT and neurologic examination. Serum S100B protein, a bio-marker for ischemic stroke, is needed as an additional diagnostic aid in acute ischemic stroke.
METHODS
We retrospectively reviewed 50 patients diagnosed with ischemic stroke between August 2007 and December 2008 by brain MRI after brain CT and serum S100B measurement in the emergency department. The serum levels of S100B protein were analyzed and the diagnostic sensitivity of non-contrast brain CT combined with abnormal elevation of S100B protein was compared with that of non-contrast brain CT alone.
RESULTS
The overall sensitivity of non-contrast brain CT in the diagnosis of ischemia was 54%. S100B protein in early ischemia had a sensitivity of 58%. However, combining non-contrast brain CT and S100B increased the sensitivity to 74%.
CONCLUSIONS
A biomarker-based diagnostic test would not replace the necessity for CT or other early imaging studies, and before contemplating any reperfusion strategy, neuro-imaging must be performed to rule out intracranial hemorrhage. However, S100B protein, a serum bio-marker, is able to help emergency physicians evaluate patients with suspected ischemic stroke and decide on treatment.
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Development of Assessment Tools for Performance and Leadership of a Cardiopulmonary Resuscitation Team
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Sung Pil Chung, Junho Cho, Yoo Seok Park, Hyung Goo Kang, Seung Whan Kim, Chan Woong Kim, Yoo Sang Yoon, Keun Jeong Song, Hoon Lim, Gyu Chong Cho, Young Hwan Choi
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Korean J Crit Care Med. 2009;24(2):64-68.
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DOI: https://doi.org/10.4266/kjccm.2009.24.2.64
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Abstract
PDF
- BACKGROUND
The assessment tools for leadership and performance of resuscitation teams are have not been developed. We evaluated the checklists for resuscitation team performance and teamwork.
METHODS
We developed two checklists for team dynamics (D1, D2) and two checklists for team performances (P1, P2). The videotaped mock resuscitation before and after a 2-hr Advanced Cardiovascular Life Support (ACLS) training were also evaluated by two emergency physicians and two nurses using the four checklists. The validity and agreement between assessors were determined. Internal consistency was determined using Cronbach-alpha.
RESULTS
There were no significant differences in scores by expert consensus and the checklist score. The average scores between different assessors were different except for the D1 and D2 between doctors. The Cronbach-alpha for internal consistency were within acceptable ranges in the checklists D2 and P2.
CONCLUSIONS
This study suggests that the D2 and P2 checklists are provisionally acceptable due to relatively high validity, agreement, and internal consistency. However, further research is needed to develop validated checklists for resuscitation teams.
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Citations
Citations to this article as recorded by  - Effects of communication team training on clinical competence in Korean Advanced Life Support: A randomized controlled trial
Soyeon Yun, Hyeoun‐Ae Park, Sang‐Hoon Na, Hee Je Yun
Nursing & Health Sciences.2024;[Epub] CrossRef - Focused and Corrective Feedback Versus Structured and Supported Debriefing in a Simulation-Based Cardiac Arrest Team Training
Ji-Hoon Kim, Young-Min Kim, Seong Heui Park, Eun A Ju, Se Min Choi, Tai Yong Hong
Simulation in Healthcare: The Journal of the Society for Simulation in Healthcare.2017; 12(3): 157. CrossRef - Nurses' Cardiopulmonary Resuscitation Performance during the First 5 minutes in In-Situ Simulated Cardiac Arrest
Eun Jung Kim, Kyeong Ryong Lee, Myung Hyun Lee, Jiyoung Kim
Journal of Korean Academy of Nursing.2012; 42(3): 361. CrossRef - Assessment and Training of Teamwork and Leadership for Critical Care Nurses: A Pilot Study
Hyun Jin Kim, Sang Mo Je, Hyun Soo Chung, Sung Phil Chung, Hahn Shick Lee
Korean Journal of Critical Care Medicine.2012; 27(2): 75. CrossRef
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